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Pentobarbital was Employed in a U.S. execution for The 1st time in December 2010 in Oklahoma, as Portion of A 3-drug protocol.[16] In March 2011 pentobarbital was employed for The 1st time as the only drug inside of a U.S. execution, in Ohio. Given that then a number of states as well as the federal federal government have made use of pentobarbital